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Sleep Apnea Treatment

CPAP vs
Inspire Therapy

If you've struggled to tolerate CPAP, Inspire offers a different path to treating obstructive sleep apnea — no mask, no hose, no machine. Here's how the two treatments actually compare.

Understanding the Differences

Two Approaches to Treating Obstructive Sleep Apnea

CPAP and Inspire are both effective treatments for obstructive sleep apnea — they just work very differently. CPAP keeps your airway open from the outside using pressurized air delivered through a mask. Inspire keeps it open from the inside using gentle nerve stimulation to move your tongue forward while you sleep.

CPAP is the gold-standard first-line therapy for moderate-to-severe sleep apnea. When it's tolerated and used every night, it's the most effective treatment available. The challenge: many patients can't tolerate the mask, hose, or noise — and stop using it within months.

Inspire is FDA-approved specifically for patients who cannot tolerate or do not benefit from CPAP. A small device implanted under the skin of the upper chest stimulates the hypoglossal nerve during sleep, gently moving the tongue and airway muscles forward. You turn it on with a small remote at bedtime — no mask, no hose, no machine. Capital ENT has performed Inspire surgery for over 10 years.

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Side-by-Side Comparison

CPAP vs Inspire

How the two treatments compare across the factors that matter most to patients.

CPAP Inspire
Type ▸ Non-surgical, nightly device ▸ Implanted device, one-time surgery
How It Works ▸ Pressurized air via mask ✓ Nerve stimulation, internal
Mask & Hose ✗ Required ✓ None
Effectiveness (when used) ✓ Gold standard ✓ ~78% median AHI reduction (STAR trial)
Real-World Adherence ✗ ~50% of patients stop using ✓ High — single button at bedtime
Sleep Apnea Severity ✓ Mild to severe ▸ Moderate to severe (AHI 15–65)
BMI Requirement ✓ None ▸ Under 40
Travel-Friendly ▸ Portable, but bulky ✓ Just the pocket-sized remote
Up-Front Procedure ✓ None — start immediately ✗ Outpatient surgery + DISE
Battery / Maintenance ▸ Replace mask + filters; no battery ▸ Battery lasts ~11 years; outpatient swap
Insurance Coverage ✓ Widely covered ✓ Covered by most major plans (incl. Medicare) when CPAP has failed

Inspire isn't a replacement for CPAP — it's an option when CPAP isn't working. Capital ENT's sleep team will review your sleep study and CPAP history to determine which is right for you.

Watch & Learn

An Inspire Patient's Story

Hear from a Capital ENT patient who couldn't tolerate CPAP and chose Inspire instead. They describe life before and after — and what the surgery and activation experience were actually like.

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Common Questions

CPAP vs Inspire FAQs

CPAP (Continuous Positive Airway Pressure) is a non-surgical therapy that uses a mask and machine to deliver pressurized air through the airway during sleep, keeping it open. Inspire is an FDA-approved implantable device — placed under the skin of the upper chest during a short outpatient procedure — that stimulates the hypoglossal nerve to keep the airway open from the inside. With Inspire, there is no mask, no hose, and no machine; patients turn it on with a small remote at bedtime.
When used consistently, CPAP remains the most effective treatment for obstructive sleep apnea. The catch is that many patients can't tolerate the mask and stop using it — making real-world effectiveness much lower. Inspire is specifically designed for those patients. In the STAR trial (the pivotal Inspire clinical study), appropriately selected patients had a median 78% reduction in apnea-hypopnea index after one year, with substantial improvement in snoring reported by bed partners.
Inspire is FDA-approved for adults with moderate-to-severe obstructive sleep apnea (AHI 15–65) who cannot tolerate or do not benefit from CPAP. Candidates should have a BMI under 40. A Drug-Induced Sleep Endoscopy (DISE) is required to confirm the airway collapses in a pattern that responds to nerve stimulation — patients with complete concentric collapse at the palate level are not good candidates. Your ENT physician will review your sleep study results, medical history, and CPAP history during a consultation.
Most major insurance plans, including Medicare, cover Inspire therapy when medical criteria are met. Coverage typically requires a documented diagnosis of moderate-to-severe obstructive sleep apnea and evidence that CPAP has been tried without adequate success or tolerance. Capital ENT's team verifies insurance benefits and obtains any necessary authorizations before scheduling surgery.
Reviewed by Dr. Zachary Wassmuth, Board-Certified Otolaryngologist

Ready for a Sleep Apnea Treatment That Works for You?

Schedule a consultation with Capital ENT's sleep team — over 10 years of Inspire experience, with full evaluation of every treatment option. Same-day and next-day appointments often available at our four Central Texas locations.

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